IMMEDIATE RESULTS OF LAPAROSCOPIC SLEEVE RESECTION OF THE GASTRICITY IN COMORBID COURSE OF OBESITY AND TYPE 2 DIABETES MELLITUS

Annotation

Resume.

Goal.

To evaluate the impact of laparoscopic sleeve gastrectomy on body weight, glucose metabolism, and remission rates of type 2 diabetes in patients with morbid obesity.

Material and methods.

A prospective observation was conducted on 59 patients with obesity and type 2 diabetes. Twentysix patients underwent laparoscopic sleeve gastrectomy (study group), while 33 patients received conservative therapy including lifestyle modification and medication (control group). Assessments included body mass index (BMI), fasting glucose, glycated hemoglobin (HbA1c), HOMAIR, and lipid profile before surgery and at 12 months followup. These data demonstrate a comprehensive improvement in the metabolic status of patients after laparoscopic sleeve gastrectomy compared with conservative therapy: significant weight loss, normalization of carbohydrate metabolism, improvement of the lipid profile, and a high rate of remission of type 2 diabetes. The results of the study confirm the high efficacy of laparoscopic sleeve gastrectomy in achieving weight loss and improving carbohydrate metabolism in patients with morbid obesity and type 2 diabetes. A significant decrease in body mass index (from 46.3 to 29.8 kg/m²) over 12 months after surgery demonstrates a significant advantage of surgical intervention over conservative therapy, where the reduction in BMI was moderate (from 44.2 to 39.9 kg/m²).

Results.

Patients in the study group demonstrated significant reductions in BMI (46.3 → 29.8 kg/m²), normalization of fasting glucose and HbA1c (11.0 → 6.1 mmol/L and 9.3% → 5.9%, respectively), improvement in HOMAIR (7.9 → 3.3), and favorable changes in lipid profile. The control group showed only moderate improvements without achieving full diabetes remission.

Conclusion.

Thus, laparoscopic sleeve gastrectomy is an effective method for weight loss and correction of metabolic disorders in patients with morbid obesity and type 2 diabetes, surpassing the results of conservative treatment.

Keywords

obesity morbid obesity type 2 diabetes bariatric surgery metabolic syn-drome body mass index (BMI).

Full text

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